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37 minutes ago, ovweather said:

Trump is cleared to resume a normal schedule without word if he’s still positive or now negative for the virus. The WH has set such a horrible example of how to handle the virus, how in the world can we expect EVERYONE to want to follow the rules now?

My non-medical professional parsing of his doctor's letter is that he still has detectable virus in his system, but is not a transmission risk due to the level and time elapsed since onset of symptoms. But who knows. 

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57 minutes ago, Hoosier said:

My non-medical professional parsing of his doctor's letter is that he still has detectable virus in his system, but is not a transmission risk due to the level and time elapsed since onset of symptoms. But who knows. 

I wouldn't trust anything said by any of them at this point. They weren't honest from the get go. Even if logic says he isn't contagious doesn't mean there isn't others who are and doesn't mean he is symptom free. Honestly at this point any sense of normalcy would be great but I don't see that coming any time soon.

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17 minutes ago, Stebo said:

Expect rises in Texas.

I know that kids were being tested before being allowed on campuses in August, but I wonder if there is any plan to test them right before they go home for the holidays.  Or if the attitude will be "who cares, not our problem anymore"

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8 hours ago, Stebo said:

HCQ has only been proven to have any usefulness in the very first few days of the virus impacting the body and even then it isn't some sort of cure but a treatment to help fight the virus when combined with zinc or steroids. By the time most people find out they are sick its too late for it to be used.

Just as a correction, there have been no RCT studies that have proven usefulness in any way for hydroxychloroquine.

None.

Not early, not during the inflammatory phase, not as a prophylactic. None. Never. No benefit.

This dude popping in here criticizing the UK study that was just published in the nejm has no clue what he's talking about at all. He's completely wrong about their methodology and is equating the first of hydroxychloroquine with chloroquine. They are different drugs, dosed differently.

Here's a link to the UK study https://www.nejm.org/doi/full/10.1056/NEJMoa2022926

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17 hours ago, ikcarsky said:

And you know this for sure?  Then maybe you can explain something to me.  The CDC relies heavily upon the results of the UK HCQ RECOVERY trial in recommending against the use of HCQ.  The CDC also just paragraphs later mentions 1.2 g in 24 h is a toxic dose of chloroquine (which is correct, and 2.0 g is often a lethal dose).  So why I should I not discard the results of the UK RECOVERY investigation when they administered 2.4 g of HCQ in the first 24 h? And to gravely ill patients no less -- is that not absurd, when the hypothesized antiviral mechanism is inhibition of viral RNA replication, and should thus be studied principally in prophylaxis?  Randomized and controlled means little when the study methodology is flawed.

Or do you just know this because you this is what the mainstream media and their associated lab coat-wearing individuals told you to think, and if you question them you're a science denier?

You do understand the dosing for hydroxychloroquine is different from chloroquine, right? .... Right?

You understand the UK study wasn't looking at chloroquine at all, right? Your concerns about toxic doses of a drug not even being studied makes you look like an idiot. You understand this?

The drug doesn't work, it just doesn't, sorry.

I prescribe hydroxychloroquine for a handful of neurologic diseases it can be a useful drug and generally well tolerated. It just doesn't work against covid. There isn't enough zinc and ionophore magic that you can wish upon it for it to work. Give it up. Move on. 

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I know that kids were being tested before being allowed on campuses in August, but I wonder if there is any plan to test them right before they go home for the holidays.  Or if the attitude will be "who cares, not our problem anymore"

Haha I’d be shocked if any SEC school tested before students returned.

Like I said, I fully expected SEC stadiums to look like that. No one has cared about this pandemic since June when the numbers got really high.

In SC we had a few days about 2,000 new cases because spread is so bad on campuses
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2 hours ago, nwohweather said:


Haha I’d be shocked if any SEC school tested before students returned.

Like I said, I fully expected SEC stadiums to look like that. No one has cared about this pandemic since June when the numbers got really high.

In SC we had a few days about 2,000 new cases because spread is so bad on campuses

Having this debate with a few friends. The Ontario government has restricted in the big cities things like restaurants, gyms, museums, weddings etc.. A lot of the industry has taken to social media saying its not their fault its schools, construction, ect.. 

If Ontario kept them open but said okay the fine for not adhering to the rules will now be a 500K fine and closure for 1 month. Do you think they would be happy since apparently they are all following the rules, or do you think they would balk at it and say no way. 

Generally curious in what peoples opinions are. I personally think the businesses would freak out and balk but that's just me, some friends said the businesses would gladly take that deal. 

 

I also want to point out that were not communists up here that drive box cars and listen to whatever the government says haha. Ontario citizens are starting to debate and "break" the covid laws like what's happening in the US. (not the crazy right wing stuff, that wouldn't fly here haha) 

https://www.cbc.ca/news/canada/hamilton/hamilton-police-ancaster-parking-lot-car-show-1.5731583

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3 hours ago, mattb65 said:

You do understand the dosing for hydroxychloroquine is different from chloroquine, right? .... Right?

You understand the UK study wasn't looking at chloroquine at all, right? Your concerns about toxic doses of a drug not even being studied makes you look like an idiot. You understand this?

The drug doesn't work, it just doesn't, sorry.

I prescribe hydroxychloroquine for a handful of neurologic diseases it can be a useful drug and generally well tolerated. It just doesn't work against covid. There isn't enough zinc and ionophore magic that you can wish upon it for it to work. Give it up. Move on. 

You are right; I should have been more careful.  Still, the medicinal effects of CQ and HCQ are very similar (as are the molecules, a single hydroxy group makes the difference.  Even the CDC page I linked lumps them together) and I at some point I began to assume equivalency in all respects.  I looked into this a bit more and it appears HCQ is favored in modern times because the hydroxy group reduces the toxicity.  Thanks for pointing that out.

Having said that, the dosing in the UK RECOVERY trial (2.0 g in first 12 h, 0.4 g every 12 h for up to 9 days after that) still appears high to me.  For acute malaria treatment, 1.6 g in first 24 h/2.0 g total in 48 h is standard; for prevention, the standard is merely 0.4 g per WEEK.  Human toxicity studies are lacking (at least from what I could find) but if HCQ is really 2-3 times less toxic than CQ that puts a toxic dose of HCQ at around 3.0 g/24 h, thus the RECOVERY trial dosing is still cause for concern, especially given the long half-life of HCQ, many weeks.  But it no longer seems maliciously bad.  Good job.

Not giving up on it though.  Lots of publications now supporting my claim about the benefits of early administration.  The first one linked therein, Ladapo et al., is a meta-analysis of five RCT studies.  24% reduction in cases found, p < 0.05, tells me HCQ works.  And those studies were without regard to zinc, but I guess that's just magic to you.

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Was reading about a documented reinfection in Israel.  Someone had it in April and then again in August.

Obviously we are learning in real time, but the issue of immunity seems like a complex thing that depends on many factors, such as a person's overall immune health to severity of the first infection to how much virus that a person is exposed to, among other things.  There is probably a good chance that most people who have had it are essentially protected for a while, but what is "a while?"  

I think there are considerably more reinfections out there that haven't been able to be documented, partly because so many cases were missed earlier on.

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26 minutes ago, Hoosier said:

Was reading about a documented reinfection in Israel.  Someone had it in April and then again in August.

Obviously we are learning in real time, but the issue of immunity seems like a complex thing that depends on many factors, such as a person's overall immune health to severity of the first infection to how much virus that a person is exposed to, among other things.  There is probably a good chance that most people who have had it are essentially protected for a while, but what is "a while?"  

I think there are considerably more reinfections out there that haven't been able to be documented, partly because so many cases were missed earlier on.

I think another question is of those reinfected are they having severe cases or just mild effects the second time around. The immune system does create memory cells capable of producing more antibodies to a specific antigen its been exposed to previously.  

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12 minutes ago, Hoosier said:

Good chance I won't be able to freely travel to Chicago soon.

https://fox59.com/news/coronavirus/chicago-residents-urged-not-to-travel-to-indiana-amid-surge-in-coronavirus-cases/amp/

Could be a bigger problem for me if it becomes a statewide policy because I cross the border into Illinois somewhat regularly.

I don't blame them with your state having such relaxed policies right now.

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13 minutes ago, Hoosier said:

Good chance I won't be able to freely travel to Chicago soon.

https://fox59.com/news/coronavirus/chicago-residents-urged-not-to-travel-to-indiana-amid-surge-in-coronavirus-cases/amp/

Could be a bigger problem for me if it becomes a statewide policy because I cross the border into Illinois somewhat regularly.

there's no enforcement on the policy though.

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5 minutes ago, Chicago Storm said:

there's no enforcement on the policy though.

Might as well not have a policy like that if it's not going to be enforced.  Unless they are hoping that a mere announcement would dissuade some people from coming in.

There would have to be all kinds of exemptions anyway.  What about people who live in Indiana and work in Chicago? 

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1 hour ago, Hoosier said:

Someone died after getting reinfected.  This is the first such documented instance.  She had leukemia, but it was treatable, so the cause of death is being attributed to covid-19.

https://metro.co.uk/2020/10/13/covid-patient-becomes-first-in-world-to-die-after-being-reinfected-13414646/

Terrible story.  But I wonder if hospitals are attributing/classifying more deaths to COVID since receive $13k per person from the government. Healthcare is big business... Cleveland Clinic was running a $44 million dollar deficit -- now they are encouraging patients to come back for routine health visits. 

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1 hour ago, NEOH said:

Terrible story.  But I wonder if hospitals are attributing/classifying more deaths to COVID since receive $13k per person from the government. Healthcare is big business... Cleveland Clinic was running a $44 million dollar deficit -- now they are encouraging patients to come back for routine health visits. 

Ya I've wondered the same, but seems most want to discount that to a conspiracy theory..

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On 10/10/2020 at 9:13 PM, nwohweather said:


Don’t really understand this reaction or comment. Government here is so limited they don’t even have an official state ban on indoor smoking. Only thing this state cares about is liquor, casinos and abortion

Limited government is a good thing!

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Guest ovweather
23 minutes ago, Nickysixes said:

This info suggests the mask mandates are here to prolong the silly "Covid" crisis...

https://thefederalist.com/2020/10/12/cdc-study-finds-overwhelming-majority-of-people-getting-coronavirus-wore-masks/

How many in the study wear masks when around family and friends because that’s where many people are picking up the virus, not from their outing to the grocery store where they are wearing a mask. Plus, trusting people’s honesty on mask wearing for a study is ridiculous. How do the researchers really know they even wore a mask all the time and if so, wore it correctly?

I’m wondering if these anti-maskers also advocate for not wearing a condom because they really don’t prevent pregnancy (and disease).

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On 10/10/2020 at 10:39 PM, ovweather said:

Trump is cleared to resume a normal schedule without word if he’s still positive or now negative for the virus. The WH has set such a horrible example of how to handle the virus, how in the world can we expect EVERYONE to want to follow the rules now?

Looks like he's now tested negative.  Great news!

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What really pisses me off about people who deny the benefit of wearing masks is that it's so obvious that they work. Like Christ. Put one on, light a candle, and try to blow it out. You won't be able to. It's really that simple to understand how face masks work. They absorb the larger, more dangerous water droplets from your breath and limit the range of the smaller ones. You really don't need a study to prove that wearing face masks is beneficial. If it were a "hoax" then why the hell are "surgical masks" even a thing? 

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The whole mask argument just won't quit.  Anti-maskers keep flaunting "studies" that show that masks don't work, while ignoring the fact that the medical profession has worn them for many years due to their effectiveness.

I feel like the problem is that the public thinks they are safe if they have their mask on when around people who aren't wearing them and therefore do not worry about social distancing.  That, combined will improper mask usage, leads to virus spread.  I see dozens of people every day wearing a mask and not having their nose covered. Why even bother wearing one if you're going to do that?  I'm positive that some of these same people are the ones who claim that they contacted COVID even though they wear a mask.

 

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