WhitinsvilleWX

It’s called conditioning. It’s really powerful. It’s really easy to condition a whole society to do things they normally wouldn’t even dream of doing. And this didn’t take long. Maybe now you younger folks see why us old boomers were and still are a little worried.

Yup They tout open floor plans as “ more conducive to collaboration”. Bullshyte. They can put double the number of people into the same square footage.

I worked for Millennium back in the day. We never hoteled. It’s a pretty newer thing at least in pharma. Although Astra Zeneca has been doing it for a few years. The open concept sux. Nobody likes it. They build “huddle rooms” on each floor. Maybe 10 -15 that have a big tv to plug into for power points etc and to have 1:1 conversations that you would normally have in an office. They’re even getting rid of all our office desk phones.

I need to go today to the one in Oxford. I’ll report back

I dunno really. I guess people are used to it and are reluctant to come back. The message from corporate is a hybrid model in the fall. 2-3 days in office and 2-3 days at home. They’re going to desk hoteling too. We all get these little 2 drawer cabinets on wheels where we keep our stuff and you will roll those to an alcove every night and sign up for a desk space. That won’t work for my group since we have oversized 32” monitors for sone specialized software and analysis. I’m trying to get assigned seating for my group. It’s not like we work in legal or accounting and can plug in anywhere. Faceless corporate crap with no personalized workspace.

Yea, for sure. First long weekend where restaurants and bars do a big business (and can be at full capacity ) and outdoor activities commence and we get this abomination.

I’m still at 46 with a stiff breeze. Had 1.4” overnight. I expect my hood doesn’t break 50 today.

Yes. And especially so since we are all supposed learned biologists. At this point it has zero to do with science and everything to do with appearances. The positivity rate in Massachusetts is below 1%. We’ll hit 70% fully vaxed in another month or so. Like I said, once we get past security and do the health attestations we basically ditch them. The only people on the floors are lab people. The rest of the office people have been told to expect to work from home until fall. And for our building it will most likely be spring. Our 7 floor building is having the offices on 2-5 renovated to open concept that won’t be done till March. The lab folks from those floors have to hotel on 6 and 7 since those are renovated already. We still have distancing requirements.

We still have to wear it at work. We’re all hoping it comes off soon. The truth is once we get into the building and up to our floor, we all pretty much kinda pull them down a little. At this point its pretty much for show. My department of 10 are the only ones on the floor and we’re all fully vaxed.

I caused it. I just bought a new WiFi Rachio irrigation controller. Guess it’s a good inside job to install it tomorrow. fail.

Yea, it’s over. Thank god for Verdugo. Right before he hit it, I told my wife he needs to hit a 3 run Johnson.

Few years ago I was running a golf tourney fund raiser for my kids school. June 1, 2015. 47 and pounded rain. Memorial Day around here can be hit or miss. I personally hate it. Warm season is short enough to have to deal with this. I suck it up and wear a hoody with my shorts and flip flops. After mid May I ain’t wearing long pants until late October unless I’m at work.

No kidding. Highway robbery. The general public has zero idea how much it cost to do biological drug R&D

I bought 5 monoclonal antibodies to try and format a CCR7 IHC assay yesterday. $500 a piece for 2 micrograms quantities. I’m sure only one will work and we’ll pitch the rest.

Pharma is not a non profit. Some companies have done some shitty stuff over the years and we pay for it through public perception. And by the way, people can put some of the blame for high drug prices on hospitals and clinical institutions as well. Why do you (not you per se but the royal you)think drugs cost so much? The average clinical trial cost ~$50,000 per patient. That’s paid directly to the hospital or clinic running the trial by the sponsoring pharma company. Clinical trials are outrageously expensive. My lab disposable/reagent budget runs $70,000 a month. And I only have 6 FTE in the lab. Science cost a LOT of money.

I do t think it has much to do with brand. I had Moderna and it was not zero, but minimal. A women who works for me had Pfizer and she was laid out for 3 days.

And that’s the main reason I got the vaccine. I’m sure I’d have been just fine. But you never know.

Hmmm. Good question. I dunno the answer to that. I’ve just never seen a lawn do really well without decent irrigation.

Your problem is water. If you don’t water a lawn, it’ll burn, get bare spots, then weeds. You’ll never keep a decent lawn without irrigation. You’re wasting money unless you keep it watered with an irrigation system. Using a sprinkler here and there you might as well be pi$$ing in the wind.

My dad used Hardy siding.

This is awful. But somehow I think the phrase "Aint happnin' James" might live on in his memory

A lot of it goes like this. A big fat fook that weighs 400 pounds needs a bypass. Dies on the table. Family sues, jury feels sorry, awards a few million. Everybody wants a perfect outcome. Not possible. And yes, failure to diagnose is a catch all. A lot of its shyte. But there’s bad physicians just like there’s bad lawyers, engineers, teachers, etc.

Now see, you just googled that and found that as a headline google search. Some “medical malpractice” isn’t really that at all. Docs will settle because it’s cheaper than going to trial. And yes, I’ve known some MDs I wouldn’t let work on my dog.

Medicine is actually pretty straightforward. TV shows makes it look like there’s all this voodoo and differential diagnosis stuff that goes on. Eh…not really. As far as scientific papers go, they really arent meant for the general public to read and interpret. I dont mean that to come off elitist. People can read them all they want. But throwing a couple papers up they googled while drinking a beer after dinner and saying, ah hah, can be misleading and not really saying what they think it says. Biology is really complicated and nuanced. A lot of these papers need context, what has come before, knowledge of the biology being discussed, how a small set of experiments or observations described fit into the area of biology being discussed etc. Anybody can google up Pubmed and pull stuff up but sometimes what is presented in the paper needs a ton of prior knowledge to really understand it. I’ve been at this more years than I care to count and there’s still stuff I read that’s pretty dense and makes me actually go back and read some of the reference papers to understand what the manuscript is trying to convey. And the way, the run of the mill MD knows shyte about science and research. Folks around here have a different perspective. We’re in the number 1 area for MD scientists in the US. A lot of MDs do research and are really good scientists. Especially pathologists and oncologist. But the reality is most MDs are clueless. Sure they might be good surgeons, best in the profession. But a lot of MDs know squat about biology. My wife’s OB/GYN is a good clinician and knows how to do a c-section, but she was an English major who took enough biology to get into med school. Once they get there, they get very little biology, immunology, etc. My dads a plumber, but I promise you I could teach him a little anatomy, watch me do it, and I’d have him doing general surgery removing an appendix a gall bladder, or resecting a cancerous bowel pretty quick.

He knows what he’s doing. I always liked doing them. Really satisfying pulling that out with the forceps and showing the patient what was causing all that pain. Sometimes it’s just a little sliver but they can make a grown man cry. Most of the ones I’ve done have been in women. They insist on wearing ill fitting heels. My buddy is an orthopedic surgeon. He does more bunion surgery on women who wear tight heels than he does knee replacements..